In vitro cytotoxicity of gold nanorods in A549 cells.

Ying Tang,Yafeng Shen,Libin Huang,Gaojian Lv,Changhai Lei,Xiaoyan Fan,Fangxing Lin,Yuxia Zhang,Lihui Wu,Yongji Yang

Environmental Toxicology and Pharmacology（2015）

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摘要

•The interaction between gold nanorods and A549 cells was investigated.•Gold nanorods had toxicity on A549 cells in a dose-dependent manner.•Gold nanorods damaged cell membrane integrity of A549 cells.•The reactive oxygen species (ROS) generation in A549 cells was induced by gold nanorods.

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关键词

Gold nanorods,A549 cells,Laser scanning confocal microscope (LSCM),Transmission electron microscope (TEM),Cytotoxicity

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