Evolving Important Role Of Lutetium-177 For Therapeutic Nuclear Medicine

CURRENT RADIOPHARMACEUTICALS(2015)

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摘要
Lutetium-177 (Lu-177) is a late entrant into the nuclear medicine therapy arena but is expected to become one of the most widely used therapeutic radionuclides. This paper analyses the reason for the increasing preference of Lu-177 as a therapeutic radionuclide. While the radionuclidic properties favor its use for several therapeutic applications, the potential for large scale production of Lu-177 is also an important aspect for its acceptability as a therapeutic radionuclide. This introductory discussion also summarizes some developing clinical uses and suggested future directions for applications of Lu-177.
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关键词
Antibodies,bone pain palliation,isotope production,Lutetium-177,peptides,targeted radionuclide therapy,therapeutic radiopharmaceuticals
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