Multiple symmetric lipomatosis: a rare disease and its possible links to brown adipose tissue.
Nutrition, Metabolism and Cardiovascular Diseases（2015）
Abstract
•Multiple Symmetric Lipomatosis (MSL) is a rare disease mostly affecting heavy drinking men.•Clinical features: symmetrical distribution and mediastinal occupation by lipomatous tissue.•Typical metabolic abnormalities: hyper-α-lipoproteinemia with high lipoprotein-lipase activity.•MSL could be the result of a disorder of proliferation and differentiation of BAT.
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Key words
Rare diseases,Lipomatosis,Brown adipose tissue,UCP 1,Lipoprotein-lipase,Hyper-alpha-lipoproteinemia
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