DLEC1 is not silenced solely by promoter methylation in head and neck squamous cell carcinoma

Didem Seven,Elif Yavuz,Erkan Kilic,Elif Baltaci,Emin Karaman,Turgut Ulutin,Nur Buyru

Gene（2015）

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摘要

Different types of genetic and epigenetic changes are associated with HNSCC. The molecular mechanisms of HNSCC carcinogenesis are still undergoing intensive investigation. The Deleted in lung and esophageal cancer 1 (DLEC1) gene is frequently silenced by methylation in various kinds of cancer. However, there is no data in the literature investigating the DLEC1 gene in the HNSCC.

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关键词

HNSCC,DLEC1,TSGs,HPV,qRT-PCR,mRNA,MSP

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