No support for replication of the genetic variants identified by a recent mega-analysis of the treatment response to antidepressants
Journal of Human Genetics(2015)
Abstract
Antidepressants are the most commonly used treatment for patients with major depressive disorder (MDD). The remission rate, however, is insufficient; approximately one-third of patients taking these medications are considered to be ‘treatment resistant’. In addition, poor response or delay in finding an appropriate drug has a negative impact on the therapeutic effect.
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Key words
Genome-wide association studies,Human Genetics,Molecular Medicine,Gene Function,Gene Expression,Gene Therapy
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