Integrative analysis of haplotype-resolved epigenomes across human tissues

NATURE(2015)

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摘要
part of the Epigenome Roadmap project, this study uses a chromosome-spanning haplotype reconstruction strategy to construct haplotype-resolved epigenomic maps for a diverse set of human tissues; the maps reveal extensive allelic biases in chromatin state and transcription, which vary across individuals due to genetic backgrounds.
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关键词
Epigenomics, Epigenetics, Gene regulation, Gene expression
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