Intraperitoneally administered biliverdin protects against UVB-induced skin photo-damage in hairless mice.

•We examine the protective effect of biliverdin on skin photo-damage in hairless mice.•We observe the clinical and histopathological changes of mouse skin.•Biliverdin inhibits the oxidative stress and the release of inflammatory factor.•Biliverdin may act on different levels of cell signaling.