Common genetic variant on BMP4 contributes to colorectal adenoma and cancer: A meta-analysis based on 15 studies.
Cytokine(2015)
Abstract
•BMP4-rs4444235 contributes to both colorectal adenoma and colorectal cancer risk.•BMP4-rs4444235 confers its CRC risk mainly in Caucasians and East Asians.•BMP4-rs4444235 conferred its effect primarily in rectal tumors.
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Key words
14q22.2–rs4444235,BMP4,Colorectal cancer,Colorectal adenoma,Meta-analysis
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