Hexa-acylated LPS-lipid A deploys the appropriate level of fibrin to confer protection through MyD88.
International Journal of Infectious Diseases(2015)
Abstract
•Fibrin has been demonstrated to function protectively against pathogens in previous studies, but a very high level of fibrin played a negative role during some infections.•An appropriate fibrin level performs critical protective roles during defense against plague, revealing the “double-edged sword” characteristic of fibrin during infections.•We demonstrated that the appropriate level of fibrin formation was deployed by hexa-acylated LPS-lipid A through myeloid differentiation factor 88.
MoreTranslated text
Key words
Lipopolysaccharide,fibrin,Yersinia pestis,coagulation
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined