Bone Metastasis in Renal Cell Carcinoma is Preprogrammed in the Primary Tumor and Caused by AKT and Integrin α5 Signaling

Tobias Haber,Elke Jöckel,Frederik C. Roos,Kerstin Junker,Dirk Prawitt,Christian Hampel,Joachim W. Thüroff,Walburgis Brenner

The Journal of Urology（2015）

引用 30|浏览8

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摘要

We describe evidence that molecular predispositions determine the potential for bone metastasis to develop in renal cell carcinoma, which may serve as prognostic markers after initial tumor detection.

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关键词

kidney,carcinoma,renal cell,neoplasm metastasis,bone and bones,signal transduction

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