[Electrochemical impedance spectroscopic study of titanium in physiological environment with blood-serum protein].

PURPOSE:Electrochemical impedance spectroscopy (EIS) was employed to study the corrosion behaviour of titanium in dummy environment with blood-serum protein. METHODS:EIS of titanium in PBS and cell culture fluid was acquired by advanced electrochemical system. The characteristic of EIS-Nyquist and EIS-Bode were investigated and the equivalent circuit was used to analyze the EIS results. The data was analyzed using SPSS 11.0 software package. RESULTS:The corrosion resistance of the titanium in cell culture fluid was significantly higher than that in PBS (P<0.05). The phase angle of TiO₂-based passive film at low frequency decreased to 55° when titanium was in PBS, but 75° when in cell culture fluid. CONCLUSIONS:The blood-serum protein plays an important role in the corrosion behaviour of titanium in physiological environment.