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Coumestrol inhibits carotid sinus baroreceptor activity by cAMP/PKA dependent nitric oxide release in anesthetized male rats.

Haitao Liu,Lixuan Wang,Huijuan Ma,Rong Guo,Rongtian Kang,Jianmin Han,Zhenming Dong

Biochemical Pharmacology（2015）

Cited 5|Views22
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Abstract
Phytoestrogens could offer multiple beneficial effects on the cardiovascular system. Here, we have examined the effects of coumestrol (CMT) on carotid baroreceptors activity (CBA) and the possible mechanisms in male rats.
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Key words
Coumestrol,Carotid baroreceptor activity,eNOS,cAMP,PKA
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