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Association of TCR/CD3, PTPN22, CD28 and ZAP70 gene polymorphisms with type 1 diabetes risk in Tunisian population: family based association study.

Zouidi Ferjeni,D Bouzid,H Fourati,M Stayoussef,O Abida,T Kammoun,M Hachicha,C Penha-Gonçalves,H Masmoudi

Immunology Letters（2015）

Cited 17|Views4
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Abstract
•We investigated TCR/CD3, PTPN22, CD28, CTLA-4, and ZAP-70 polymorphisms in 59 families.•We report an association of PTPN22 and CD28 genes with risk for to T1D.•ZAP-70 and TCR/CD3 seems to contribute to the susceptibility to T1D.
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Key words
T1D,HWE,LD
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