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Personalized biomarkers to monitor disease progression in advanced non-small-cell lung cancer patients treated with icotinib.

Gaoguang Song,Yujie Liu,Yanying Wang,Guanjun Ren,Shuai Guo,Junling Ren,Li Zhang,Zhili Li

Clinica Chimica Acta（2015）

Cited 12|Views16
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Abstract
•Three characteristic patterns of plasma IIRPCs are observed.•Changes in the IIRPCs levels are closely associated with cancer development.•The TLHIIR are closely associated with cancer development.•The median TLHIIR is 22weeks, lead time of 11weeks relative to PFS.
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Key words
NSCLC,IIRPCs,TLHIIR,TLDP,EGFR,TKI
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