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Whole-Genome Sequencing Confirms That Burkholderia Pseudomallei Multilocus Sequence Types Common To Both Cambodia And Australia Are Due To Homoplasy

Birgit De Smet,Derek S. Sarovich,Erin P. Price,Mark Mayo,Vanessa Theobald,Chun Kham,Seiha Heng,Phe Thong,Matthew T. G. Holden,Julian Parkhill,Sharon J. Peacock,Brian G. Spratt,Jan A. Jacobs,Peter Vandamme,Bart J. Currie

JOURNAL OF CLINICAL MICROBIOLOGY（2015）

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Abstract
Burkholderia pseudomallei isolates with shared multilocus sequence types (STs) have not been isolated from different continents. We identified two STs shared between Australia and Cambodia. Whole-genome analysis revealed substantial diversity within STs, correctly identified the Asian or Australian origin, and confirmed that these shared STs were due to homoplasy.
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