Determination of fluoroquinolones in chicken feces - a new liquid-liquid extraction method combined with LC-MS/MS.

Environmental Toxicology and Pharmacology(2014)

Cited 53|Views11
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Abstract
•Suitable method for the detection of fluoroquinolones in the sub μg/kg range in chicken feces.•Highest analyte recoveries were achieved using dichloromethane as extraction solvent.•The use of EDTA is advisable to increase recovery and decrease matrix interactions.•High enrofloxacin amounts were excreted after a treatment with 10mg/kg bodyweight.•Intake of antibiotics below therapeutic dosages e.g. via dried feces particles is discussed.
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Key words
Fluoroquinolones,LC–MS/MS,Liquid–liquid extraction,Feces,Chicken
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