Assessment of the effects of naringenin-type flavanones in uterus and vagina.

Annekathrin Martina Keiler,Peggy Dörfelt,Namita Chatterjee,Janina Helle,Manuela I Bader,Günter Vollmer,Georg Kretzschmar,Franziska Kuhlee,Detlef Thieme,Oliver Zierau

The Journal of Steroid Biochemistry and Molecular Biology（2015）

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摘要

•8PN was slightly uterotrophic and induced gain in uterine glandular epithelial thickness in ovx rats.•Naringenin-type flavanones did not stimulate uterine cell proliferation.•Vaginal atrophy was not prevented by naringenin, 8PN or 6DMAN.

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关键词

8-Prenylnaringenin,6-(1,1-Dimethylallyl)naringenin,Naringenin,17β-Estradiol,Estrogenicity,Uterus,Vagina

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