Hyperbaric oxygen preconditioning protects lung against hyperoxic acute lung injury in rats via heme oxygenase-1 induction.
Biochemical and Biophysical Research Communications（2015）
Abstract
•HBO-PC ameliorated the biochemical and histological lung alterations induced by hyperoxia.•HBO-PC decreased oxidative products but increased antioxidant enzymes.•HBO-PC up-regulated HO-1 mRNA and activity.•HO-1 inhibitor abolished the protective effects of HBO-PC.
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Key words
Hyperoxic acute lung injury,Oxidative stress,Hyperbaric oxygen preconditioning,Heme oxygenase-1
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