Deranged liver function tests in a patient with Hodgkin's lymphoma.

•This is a case of hepatitis E in a patient with Hodgkin's lymphoma.•Diagnosis of HEV infection is unreliable in immunocompromised patients.•Detection of HEV RNA must be used in immunocompromised patients with hepatitis.•Hepatitis E can become chronic in immunocompromised patients.•The management of acute and chronic hepatitis E is reviewed.