Structural basis for the assembly of the Sxl–Unr translation regulatory complex
NATURE(2014)
Abstract
The crystal structure of the RNA binding domains of Sxl and Unr with msl2 RNA shows that interwoven interactions establish cooperative assembly of the ternary complex, highlighting how binding of relatively general RNA binding domains to RNA can result in a unique and specific protein–RNA architecture.
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Key words
X-ray crystallography, RNA-binding proteins, Translation, Developmental biology
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