Discovery of lesser known flavones as inhibitors of NF-κB signaling in MDA-MB-231 breast cancer cells--A SAR study.

Summary of the molecular (expression of MMP-9 and COX-2, and activation of NF-κB), and cellular effects (migration, invasion and cell cycle) of chrysoeriol. The black arrows indicate induction, and the grey lines indicate inhibition. The thickness of the arrows corresponds to the level of induction by PMA or doxorubicin. The numbers in the grey boxes denotes the fold induction (+), or inhibition (−).