SeqControl: process control for DNA sequencing

Lauren C Chong,Marco A Albuquerque,Nicholas J Harding,Cristian Caloian,Michelle Chan-Seng-Yue,Richard de Borja,Michael Fraser,Robert E Denroche,Timothy A Beck,Theodorus van der Kwast,Robert G Bristow,John D McPherson,Paul C Boutros

NATURE METHODS（2014）

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摘要

SeqControl uses 15 quality metrics of high-throughput sequencing experiments to predict how much sequencing is needed to reach a desired depth of coverage.

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关键词

Statistical methods, Data acquisition, DNA sequencing, Software

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