Frozen section of uterine curetting in excluding the possibility of ectopic pregnancy--a clinicopathologic study of 715 cases.

Introduction: To investigate the utility of frozen section of uterine curetting in excluding the possibility of ectopic pregnancy (EP). Materials and Methods: A retrospective analysis of 715 curetting records in the present hospital from July 1999 to May 2009 was obtained. All specimens were processed routinely with frozen section and paraffin section. Results: Of 715 cases, frozen section analyses were discordant in 33 cases (4.6%), including 32 cases under-diagnosed, and one case over-diagnosed, compared with the final diagnoses. Frozen section had a sensitivity of 92.6%, specificity of 99.6%, and frozen section accuracy rate of 95.4%. Conclusions: Frozen section is a useful and rapid method to differentiate EP from intrauterine pregnancy.