Dominant modern sublineages and a new modern sublineage of Mycobacterium tuberculosis Beijing family clinical isolates in Heilongjiang Province, China

Di Li,Cai-Bo Dong,Jia-Yi Cui,Chie Nakajima,Chun-Lei Zhang,Xin-Ling Pan,Gao-Xiang Sun,En-Yu Dai,Yasuhiko Suzuki,Min Zhuang,Hong Ling

Infection, Genetics and Evolution（2014）

Cited 8|Views20

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Abstract

•9 out of the 10 SNP loci displayed polymorphisms but locus 1548149 did not.•92.8% of the isolates in Heilongjiang Province are the modern sublineages.•ST10 is the most prevalent sublineage.•A new ST accounting for 4% of the Beijing family isolates was found for the first time in the world.•Each new ST isolate showed a unique VNTR pattern, and none were clustered.

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Key words

Mycobacterium tuberculosis,Beijing family,Single nucleotide polymorphism (SNP),Evolution,Sublineage

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