SCOPE++: sequence classification of homoPolymer emissions.

James T Morton,Patricia Abrudan,Nathanial Figueroa,Chun Liang,John E Karro

Genomics（2014）

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摘要

•Tool for collecting data necessary for study of alternative polyadenylation•First tool capable of annotating both ends of poly(A) tails in mRNA•HMM-base approached allowing for data-specific training•Near-perfect accuracy at speeds appropriate for high-throughput applications

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关键词

Polyadenylation,Transcriptome,Hidden Markov Model

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