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Rutin attenuates ethanol-induced neurotoxicity in hippocampal neuronal cells by increasing aldehyde dehydrogenase 2

Kibbeum Song,Sokho Kim,Ji-Young Na,Jong-Heum Park,Jae-Kyung Kim,Jae-Hun Kim,Jungkee Kwon

Food and Chemical Toxicology（2014）

Cited 30|Views3
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Abstract
•Rutin protects against ethanol-induced neurotoxicity through ALDH2 activity.•Rutin ameliorates mitochondrial dysfunction induced by ethanol.•Rutin inhibits apoptotic proteins induced by ethanol.
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Key words
Rutin,Ethanol,Hippocampal neuronal cells,Neurotoxicity,Aldehyde dehydrogenase 2
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