Plasminogen activator inhibitor-1 regulates infiltration of macrophages into melanoma via phosphorylation of FAK-Tyr⁹²⁵.

Bikash Thapa,Bon-Hun Koo,Yeon Hyang Kim,Hyung-Joo Kwon,Doo-Sik Kim

Biochemical and Biophysical Research Communications（2014）

引用 28|浏览2

暂无评分

摘要

•PAI-1 enhances the invasion of macrophages into melanoma.•PAI-1 induces phosphorylation of FAK at Tyr925.•FAK-Tyr925 phosphorylation is essential for such PAI-1-induced macrophage invasion.•LRP1 is essential for PAI-1-induced macrophage invasion into melanoma.

查看译文

关键词

Macrophage,PAI-1,FAK,Melanoma,Invasion,LRP1

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要