Transcriptome analysis in cardiomyocyte-specific differentiation of murine embryonic stem cells reveals transcriptional regulation network.

Gene Expression Patterns（2014）

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摘要

•Pure stem cell derived cardiomyocytes were generated and applied in this study.•Genome-wide expression profiling was performed during cardiomyocyte specific differentiation.•Key driving TFs for cardiomyocyte specific differentiation were identified.•TF regulation networks during cardiomyocyte specific differentiation were constructed.

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关键词

BP,ChIP,DMEM,EB,EGFP,ESC,FCS,GO,IMDM,ITFP,KEGG,MF,PCA,TF,α-MHC

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