Cilostazol prevents the degradation of collagen type II in human chondrocytes.

Weidong Wang,Weibiao Kang,Qiang Tang,Guanfeng Yao,Yuchun Chen,Bizhen Cheng,Kangmei Kong

Biochemical and Biophysical Research Communications（2014）

引用 8|浏览40

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摘要

•Cilostazol ameliorates the degradation of collagen type II in chondrocytes.•Cilostazol ameliorates the expression of MMP-13 induced IL-1β.•Cilostazol mitigates the upregulation of IRF-1 induced by IL-1β.•Cilostazol prevents the activation of STAT1.

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关键词

Cilostazol,Osteoarthritis (OA),Collagen type II,MMP-13,IRF-1,STAT1

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