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排名必读论文期刊顶会热点AI 简史溯源树小脉星探人才迁徙塔尖人才国防情报追踪开源工具智慧手语
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ABCB5 is a limbal stem cell gene required for corneal development and repair

Bruce R. Ksander,Paraskevi E. Kolovou,Brian J. Wilson,Karim R. Saab,Qin Guo,Jie Ma,Sean P. McGuire,Meredith S. Gregory,William J. B. Vincent,Victor L. Perez,Fernando Cruz-Guilloty,Winston W. Y. Kao,Mindy K. Call,Budd A. Tucker,Qian Zhan,George F. Murphy,Kira L. Lathrop,Clemens Alt,Luke J. Mortensen,Charles P. Lin,James D. Zieske,Markus H. Frank,Natasha Y. Frank

NATURE（2014）

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摘要
The loss of limbal stem cells (LSCs) due to injury or disease is one of the leading causes of blindness; here, the ABCB5 protein is identified as a marker of LSCs in mouse and human eye, and shown to be functionally required for LSC maintenance, corneal development and repair.
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关键词
Stem cells, Corneal diseases
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