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BDNF-mediated modulation of glycine transmission on rat spinal motoneurons.

Jian-Dong Ding,Xian-Ye Tang,Jian-Gang Shi,Lian-Shun Jia

Neuroscience Letters（2014）

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Abstract
•BDNF did not produce a direct excitatory or inhibitory effect on the motoneurons.•BDNF dose-dependently increased the glycinergic transmission in the motoneurons.•BDNF-induced enhancement of the glycinergic transmission was mediated by the activation of TrkB receptors.•BDNF and its receptors TrkB had an extensive expression in the motoneurons.
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Key words
BDNF,Motoneuron,Glycine,TrkB,Motor control
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