Structure–toxicity relationship and structure–activity relationship study of 2-phenylaminophenylacetic acid derived compounds

Yi Yun Pang,Wee Kiang Yeo,Kep Yong Loh,Mei Lin Go,Han Kiat Ho

Food and Chemical Toxicology（2014）

引用 6|浏览6

暂无评分

摘要

•Structural changes on the scaffold of interest affected in vitro liver cytotoxicity.•Higher toxicity was observed in the more metabolically competent cell line.•A safety profile for the compounds was derived using activity and toxicity data.

查看译文

关键词

(±)-BINAP,cLogP,COX,CYP,DCM,ELISA,EtOAc,IC50,LC50,LPS,MTT,NSAIDs,PGE2,RLU,TXB2

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要