睾丸原发性卵黄囊瘤临床病理分析(附8例报告)
Zhonghua nan ke xue = National journal of andrology(2014)
Abstract
目的:探讨睾丸原发性卵黄囊瘤的临床病理特征、诊断、治疗及预后. 方法:运用光镜、免疫组化对8例睾丸原发性卵黄囊瘤进行检测. 结果:8例睾丸原发性卵黄囊瘤来自我院1998 ~2013年诊治的病例(2例为外院会诊病例),占我院同期睾丸生殖细胞肿瘤的10.7%(8/75),患者年龄7~ 43岁,平均23.9岁,8例患者临床表现均为患侧睾丸无痛性肿大,均发生于单侧睾丸.组织学:全部病例肿瘤组织均见微囊或网状结构和嗜酸性透明滴,而作为本瘤结构的S-D小体有5例.8例中仅1例为单纯性卵黄囊瘤,其余7例均为混合性卵黄囊瘤.免疫表型:AFP为其特征性标记物.结论:原发于睾丸的卵黄囊瘤是罕见的恶性肿瘤,术前AFP检测有助诊断,确诊依赖于病理检查.以手术加放、化疗的综合治疗措施,可以延长生存期.
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Key words
testis,yolk sac tumor,endodermal sinus tumor,immunohistochemistry
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