Novel molecular events associated with altered steroidogenesis induced by exposure to atrazine in the intact and castrate male rat

Reproductive Toxicology(2014)

Cited 18|Views9
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Abstract
•Atrazine increases serum progesterone and corticosterone in both intact and castrate male rats.•Luteinizing hormone, androstenedione and testosterone were expressed non-monotonically.•Testicular proteins known to be regulated by ubiquitin C were expressed in a non-monotonic fashion.•Two adrenal proteins, HSPD1 and PGRMC1 were correlated; PGRMC1 correlated with testosterone.
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Key words
Atrazine,Steroidogenesis,Hypothalamic-pituitary-adrenal (HPA) axis,Corticosterone,Proteomics
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