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Inter-alpha-trypsin inhibitor heavy chain H4 as a diagnostic and prognostic indicator in patients with hepatitis B virus-associated hepatocellular carcinoma.

Choong-Kyun Noh,Soon Sun Kim,Dong-Kyu Kim,Hyun-Young Lee,Hyo Jung Cho,So Young Yoon,Gil Ho Lee,Sun A Hyun,Yu Jeong Kim,Ho Joong Kim,Joo An Hwang,Seun Joo Ahn,Sung Jae Shin,Kee Myung Lee,Byung Moo Yoo,Sung Won Cho,Jae Youn Cheong

Clinical Biochemistry（2014）

Cited 19|Views8
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Abstract
•Inter-alpha-trypsin inhibitor heavy chain H4 (ITIH4) is associated with HCC development.•Serum ITIH4 levels are reduced in HCC compared to that in CHB and cirrhosis.•Low serum ITIH4 levels are associated with shorter survival in HCC patients.
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Key words
Inter-alpha-trypsin inhibitor heavy chain H4,Hepatitis B,Hepatocellular carcinoma,Survival,Diagnosis
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