Hepatitis C virus NS5A competes with PI4KB for binding to ACBD3 in a genotype-dependent manner.

Antiviral Research（2014）

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摘要

•ACBD3 inhibited HCV replication.•ACBD3 bind to GT1b NS5A with a higher affinity than to GT2a NS5A.•NS5A and PI4KB competed for association of ACBD3.

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关键词

HCV,PI4P,ACBD3,Co-IP,GST

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