Vaccination of lambs against Haemonchus contortus infection with a somatic protein (Hc23) from adult helminths

Elshaima M. Fawzi,María Elena González-Sánchez,María Jesús Corral,Montserrat Cuquerella,José M. Alunda

International Journal for Parasitology（2014）

引用 28|浏览4

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摘要

•A protein from adult Haemonchus contortus (Hc23) has been purified.•Hc23 elicits a protective response against experimental haemonchosis in lambs.•Protection was induced with Al(OH)3 or bacterial (Propionibacterium+LPS) adjuvant.•Hc23 reduces parasite’ egg excretion (70.67–85.64%) and burdens (67.17% to >86%).•Vaccinated lambs showed significantly higher live weight gains.

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关键词

Hc23,Haemonchus contortus,Vaccination,Lambs,Native protein,Immunochromatography,Haemonchosis

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