Antrodia cinnamomea profoundly exalted the reversion of activated hepatic stellate cells by the alteration of cellular proteins

Yi-Ren Chen,Kai-Ting Chang,May-Jywan Tsai,Chia-Hung Lee,Kao-Jean Huang,Henrich Cheng,Yen-Peng Ho,Jian-Chyi Chen,Hsueh-Hui Yang,Ching-Feng Weng

Food and Chemical Toxicology（2014）

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摘要

•ACME could restore fatty acid storage in non-induced HSCs.•ACME inhibited several biomarker of the activated HSC.•Antrodia cinnamomea could use as an functional food for the prevention of liver fibrosis.

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关键词

ACME,aHSCs,DAPI,DMEM,FBS,LC,MS,MMP-2,MTS,p55,PKG-1,PMS,PPAR-γ,qHSCs,ROS,SG-II,α-SMA,SMC6,TAA

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