A novel microfluidic system for the rapid analysis of protein thermal stability.

Xin Yang,Jia Liu,Ye Lei Xie,Yang Wang,Hong Ying,Qiong Wu,Wei Huang,Gareth Jenkins

ANALYST（2014）

引用 11|浏览4

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摘要

We describe a simple microfluidic device for the rapid analysis of protein thermal stability using a novel imaging method. The change in UV absorption upon thermal denaturation or aggregation of proteins is used to get a spatial image of proteins' folding or aggregation state along a linear temperature gradient.

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关键词

novel microfluidic system,thermal stability,protein

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