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Metallothionein mRNA induction is correlated with the decrease of DNA strand breaks in cadmium exposed zebra mussels.

Françoise Vincent-Hubert,Amélie Châtel,Catherine Gourlay-Francé

Mutation Research/Genetic Toxicology and Environmental Mutagenesis（2014）

Cited 7|Views10
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Abstract
•Cadmium (Cd) and benzo[a]pyrene (BaP) induced DNA damages in zebra mussels.•Cd is a strong inducer of metallothionein (MT) and HSP70 genes.•Metallothionein might be implicated in cadmium detoxification.•BaP is a strong inducer of P-gp and AHR genes.•Cd and BaP induced in moderate changes in antioxidant enzymes mRNA.
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Key words
Benzo[a]pyrene,Cadmium,Metallothionein,Aryl hydrocarbon receptor,Antioxidant enzymes,RT-qPCR
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