Abstract 649: AT1R Blockade With Losartan Attenuates Abdominal Aortic Aneurysm Development in Spontaneously Hypertensive Mice

Nicholas D Ward,Tyler Grespin,Christine Couch,Rupak Mukherjee, Jeffrey Jones,Jean Marie Ruddy

Arteriosclerosis, Thrombosis, and Vascular Biology（2019）

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摘要

Introduction: In addition to ligand-specific activation, the Angiotensin II Type 1 receptor (AT1R) has been shown to activate under conditions of mechanical stretch. However, whether this activity ...

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aortic aneurysm,hypertensive mice,at1r blockade

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