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Intestinal autophagy activity is essential for host defense against Salmonella typhimurium infection in Caenorhabditis elegans.

Alexander Curt,Jiuli Zhang,Justin Minnerly,Kailiang Jia

Developmental & Comparative Immunology（2014）

Cited 24|Views2
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Abstract
•We examined the tissue-specific role of autophagy in defense against Salmonella.•Intestinal bec-1 activity is essential for C. elegans to defend against Salmonella.•Autophagy acts cell autonomously to fight against Salmonella in C. elegans.
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Key words
Autophagy,bec-1,Salmonella,C. elegans,Pathogen-host interaction
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