Basic Tilted Helix Bundle - a new protein fold in human FKBP25/FKBP3 and HectD1.

Sara Helander,Meri Montecchio,Alexander Lemak,Christophe Farès,Jonas Almlöf, Yanjun Yi,Adelinda Yee,Cheryl Arrowsmith,Sirano DhePaganon,Maria Sunnerhagen

Biochemical and Biophysical Research Communications（2014）

引用 14|浏览17

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摘要

•We describe the structure of a novel fold in FKBP25 and HectD.•The new fold is named the Basic Tilted Helix Bundle (BTHB) domain.•A conserved basic surface patch is presented, suggesting a functional role.

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关键词

Immunophillins,NMR structure,Structural genomics,FKBP25,FKBP3,HectD1,YY1

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