Improved detection of bacterial central nervous system infections by use of a broad-range PCR assay.
JOURNAL OF CLINICAL MICROBIOLOGY(2014)
摘要
A universal PCR assay for bacteria and fungi detected meningitis pathogens in 65% of 20 cerebrospinal fluid ( CSF) samples from patients with suspected central nervous system (CNS) infections compared to a 35% detection rate by culture and/or microscopy methods. Thus, the PCR assay can improve the diagnosis rate of infective meningitis when standard methods provide a negative result.
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关键词
bacteria,polymerase chain reaction
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