Fumonisin B₁ modulates expression of human cytochrome P450 1b1 in human hepatoma (Hepg2) cells by repressing Mir-27b.

Anil A Chuturgoon,Alisa Phulukdaree,Devapregasan Moodley

Toxicology Letters（2014）

引用 50|浏览2

暂无评分

摘要

•Fumonisin B1 significantly downregulates miR27b in HepG2 cells.•FB1, significantly upregulates CYP1B1 mRNA and protein expression in HepG2 cells.•CYP1B1 is post-transcriptionally regulated by miR-27b after HepG2 exposure to FB1.

查看译文

关键词

Fumonisin B1,MicroRNA (miR)-27b,Cytochrome P 450 (CYP1B1),Liver cancer,HepG2 cells

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要