Mitochondrial stress: balancing friend and foe.
Experimental Gerontology(2014)
Abstract
Mitochondria are vital organelles of the aerobic eukaryotic cell. Their dysfunction associates with aging and widespread age-related diseases. To sustain mitochondrial integrity, the cell executes a distinct set of stress-induced protective responses.
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Key words
Mitochondria,Aging,Stress,UPRmt,Fission–fusion
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