Association of Lp-PLA2 with digital reactive hyperemia, coronary flow reserve, carotid atherosclerosis and arterial stiffness in coronary artery disease.
Atherosclerosis(2014)
Abstract
•We investigated the association of Lp-PLA2 with prognostic vascular markers in CAD.•Lp-PLA2 was related abnormal digital reactive hyperemia and coronary flow reserve.•Lp-PLA2 was related with carotid atherosclerosis and increased arterial stiffness.•Lp-PLA2, digital reactive hyperemia and coronary flow reserve were related with prognosis at 3 years f/u.•The prognostic value of Lp-PLA2 is likely mediated by its effects on vascular properties.
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Key words
Lp-PLA2,Coronary artery disease,Reactive hyperemia index,Coronary flow reserve,Carotid intima-media thickness,Pulse wave velocity,Prognosis
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