Activity of caffeic acid derivatives against Candida albicans biofilm.

Daniela De Vita,Laura Friggeri,Felicia Diodata D'Auria,Fabiana Pandolfi,Francesco Piccoli,Simona Panella,Anna Teresa Palamara,Giovanna Simonetti,Luigi Scipione,Roberto Di Santo,Roberta Costi,Silvano Tortorella

Bioorganic & Medicinal Chemistry Letters（2014）

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摘要

The aim of this study was to evaluate the caffeic acid (1) and ester derivatives (2–10) against Candida albicans biofilm and to investigate whether these compounds are able to inhibit the biofilm formation or destroy pre-formed biofilm.

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