Spectrophotometric methods for simultaneous determination of ternary mixture of amlodipine besylate, olmesartan medoxomil and hydrochlorothiazide.

Hanan A Merey,Nesrin K Ramadan,Sherine S Diab,Azza A Moustafa

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy（2014）

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摘要

•Four simple spectrophotometric methods were successfully applied.•They are used for simultaneous analysis of complex ternary mixtures.•They are sensitive and selective and do not require sophisticated techniques.•They could be easily applied in QC labs lacking liquid chromatographic instruments.•They are used for analysis of dosage form without prior separation.

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关键词

Ternary mixture,First derivative ratio spectra,Double divisor,Successive spectrophotometry,Isoabsorptive point,Mean centering

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