The effects of administration of ligands for Toll-like receptor 4 and 21 against Marek's disease in chickens.

Payvand Parvizi,Mohamed Faizal Abdul-Careem,Amirul Islam Mallick,Kamran Haq,Hamid R Haghighi,Shahriar Orouji,Mohammad Heidari,Shahriar Behboudi,Shayan Sharif

Vaccine（2014）

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摘要

•Toll-like receptor ligands reduced incidence of MD or delay onset of this disease.•Among the ligands, LPS was the most potent to induce immunity against MD.•CpG-ODN was also able to induce immunity against MD.•Immunity was associated with expression of IFNs in spleen and lungs.

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关键词

TLR4,TLR21,Cytokines,Marek's disease,Immunity

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